Uptrend Under Pressure 93
Institutional selling is building — 7 distribution days in the last 25 sessions. Severe risk · 93/100 · 7 distribution days (SPY) Sep 11 Full briefing →
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VRTX · Vertex Pharmaceuticals Incorporated

$514.56 -1.26% Sep 10 close
Detected setup Trend Only · Setup Score 71/100

Stand aside — setup invalidated

Setup score 71, but distribution days reach 5 or more — stand aside until the condition resets.

1 independent risk warning also present. Review before relying on the bullish setup.

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$VRTX

Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated is a large-cap Pharmaceuticals: Major company in the Health Technology sector with a market cap of $130B.

Health Technology Pharmaceuticals: Major stock Stage 2 · Advancing Base 2
$514.56 latest close
Verdict · setup score 71/100 · data Sep 10 close · 1 session old

Stand aside — setup invalidated

Setup score 71, but distribution days reach 5 or more — stand aside until the condition resets.

Earnings

Normal technical setup

No sourced report date Event risk is not modelled for this symbol

Deterministic evidence

VRTX-1.26%
Sector proxy · XLV-0.55%
Broad market · SPY-0.60%
Same completed session window ending 2026-09-10. VRTX was -0.71 points vs XLV. -0.66 points vs SPY.

Session internals Weak

Rule: closed flat-to-down and in the bottom third of the range. Judged on internals, not on the size of the move.

Vs prior close-1.26% From the open-0.82% Range position3% GapNo gap
QQQ confirmationConfirming (-1.06%) SMH confirmationConfirming (-2.44%)
Price bars, sourced event fields, and benchmark math only. This can adjust displayed short-term conviction; it does not change the stored scanner score or readiness.

Ask a Legend to interpret this evidence → Commentary only — never scanner evidence or a sizing recommendation.

Price $514.56 -1.3% Sep 10 close
52W High $560.25 8.2% below high
Wks Since High 0w
Base Depth 7.8% 8.2% today
RS Rank 39 percentile of scan
SMA 50 $510.30
Avg Vol 1,290,771
Rel Vol (Sep 10) 0.63×
More stats
52W Low $374.17
Tight Wks 0
Base B2
SMA 200 $467.58
RS Line vs High -7.9%
RS Line Slope +2.3% ▲
Group Rank #27/58
ADR% 2.2%
ATR(14) $11.43 (2.2%)
Vol Pace (live) N/A
U/D Vol 0.90
A/D Days 21A / 9D
A/D Rating A+
VDU Bars 0/10 d
Position in 52-week range 75thpercentile of the 52-week range
$374.17low
$560.25high

VRTX Chart

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Technical Analysis Report Card

$VRTX · $514.56 · as of 2026-09-10 · multi-factor read
62
/ 100
Technicals 62/100
Reference read from price & volume only — the verdict at the top of the page decides the action.

Trend · Daily / Weekly / Monthly

Daily ▬ Sideways / consolidating
Weekly ▲ Uptrend
Monthly ▲ Uptrend

Moving Averages

50-day$510.30 ↑
100-day$477.11 ↑
200-day$467.58 ↑
Bullish (50 > 200)

RSI (14)

Reading43.5 · Bearish

Bearish momentum — sellers in control.

MACD (12/26/9)

StateWeakening
Histogram-5.333

Weakening — MACD slipped below its signal line. Histogram contracting.

Bollinger Bands (20,2)

%B / Width13% · 11.8%

Near the lower band — under pressure or oversold.

Volume · Buyer vs Seller

Up/Down vol0.9 · Neutral
Rel volume0.63×

Balanced — up/down volume is roughly even; no clear hand. Recent volume is easing versus its baseline.

Support & Resistance

R · $533.67swing level
R · $546.17swing level
R · $555.69swing level
Price · $514.56now
S · $467.43swing level
S · $450.67swing level
S · $431.01swing level

Fibonacci · Uptrend swing

23.6%$525.33
38.2%$503.72
50.0%$486.26
61.8%$468.80
78.6%$443.94

Retracement support zones measured from the recent swing low up to the high.

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Weekly uptrendMonthly uptrendAbove 200-day MA50/200 bullish
Want this read in a legend's voice? Ask a Legend about VRTX
Generic technical analysis generated mechanically from price & volume — educational research only, not financial advice or a personalized recommendation. Levels are illustrative; confirm on your own chart. New to these terms? →
Legend Verdicts 6 methodology checks

Who would consider this setup, why it qualifies, and what blocks it — calculated from the same deterministic methodology rules used across Legend AI.

Council consensus: 5 of 6 legends are Watching — building, not yet a confirmed buy.
Watch
Minervini C

Trend-template read: 6/10 pass; wait for the soft misses to improve.

Passing evidence
1.1 Price > 150-day MA AND 200-day MAPrice $514.56, MA150 $471.88, MA200 $467.58
1.2 150-day MA > 200-day MAMA150 $471.88 vs MA200 $467.58
Failing evidence
1.8 RS rank ≥ 70 (prefer ≥ 85)RS rank 48
2. Quarterly EPS growth ≥ 25%From SEPA scan
6/10 checks
Avoid
O'Neil D

CANSLIM read: fails C: Quarterly EPS acceleration ≥ 25%.

Passing evidence
N: Near 52-week high or RS line new high8.2% below high | RS line new high: False
S: Base tightness (ATR% ≤ 4.5%)ATR% 2.22%
Failing evidence
L: RS rank ≥ 80 (IBD leadership)RS rank 48
C: Quarterly EPS acceleration ≥ 25%Data unavailable
2/8 checks
Watch
Weinstein C

Stage-analysis read: Stage 2 is present; 2 supporting checks need improvement.

Passing evidence
Stage 2 (Advancing phase) confirmedStage 2 (Advancing)
Price above 30-week MA (200-day proxy)Price $514.56 vs MA200 $467.58
Failing evidence
Volume expansion above averageVolume ratio 0.63x
Relative strength ≥ 60RS 48
5/7 checks
Watch
Livermore B

Pivotal-point read: constructive evidence is present, but relative strength is unresolved.

Passing evidence
Price$514.56
Distance from 52-week high8.2% below high
Failing evidence
Relative strengthRS 48
Volume vs average0.63x
3/6 checks
Watch
Darvas B

Box-theory read: constructive evidence is present, but relative strength is unresolved.

Passing evidence
Price$514.56
Distance from 52-week high8.2% below high
Failing evidence
Relative strengthRS 48
Volume vs average0.63x
3/6 checks
Watch
Wyckoff B

Supply-and-demand read: constructive evidence is present, but relative strength is unresolved.

Passing evidence
Price$514.56
Distance from 52-week high8.2% below high
Failing evidence
Relative strengthRS 48
Volume vs average0.63x
3/6 checks
Base & Breakout
Breakout follow-through

No active breakout tracked — Legend AI monitors daily for pivot-point breaks. What's a breakout?

RS Line vs SPY 52-week relative strength · blue = RS line · dashed = MA50 · dot = NH ▲ Rising
114RS Line (52W)
Accumulation / Distribution last 65 sessions · green = acc on high vol · red = dist on high vol Net +8 A+
A: 18 D: 10 Net: +865 sessions
Minervini · Grade Card
Fundamentals & leadership quality — Minervini’s published criteria · 2/7 met
C 2/7 criteria
Separate score from the Minervini Trend Template (7/8): the Trend Template grades the price structure, this grades the company & leadership (earnings, sales, margins, RS rank). A stock can ride a clean trend while its fundamentals lag, so the two often differ by design — they are not the same checklist.
EPS acceleration ≥25% QoQ
Revenue growth ≥20% YoY +9%
Gross margin ≥30%
ROE ≥17%
RS rating ≥80 (leadership) 48
Stage 2 uptrend (Weinstein) Stage 2
Within 25% of 52W high -8.2%

Method Playbook

Trade it like Darvas EXACT LEVELS · PRO
Darvas B · Watch — The deterministic methodology check is Watch; wait for the failing or incomplete criteria to improve before the trigger can qualify.
Pivot
Pro level
Published-method rule: Use the top of the active Darvas box near the high as the mechanical breakout boundary.
Evidence: Canonical setup geometry is available with Pro.
Entry trigger
Pro level
Published-method rule: Require price to clear the box top with volume confirmation; movement inside the box remains observation, not a trigger.
Evidence: Canonical setup geometry is available with Pro.
Initial stop
Pro level
Published-method rule: Start below the active box support or the canonical structural stop that proves the breakout failed.
Evidence: Canonical setup geometry is available with Pro.
Trail
Rule-based
Published-method rule: As higher boxes form, raise the stop beneath the newest confirmed box floor; the stop moves up only.
Evidence: Planned management rule; no stored stop or broker order is changed automatically.
Exit / invalidation
Pro level
Published-method rule: Exit when price breaks the active box floor or decisively falls back through the breakout structure.
Evidence: Canonical setup geometry is available with Pro.
Deterministic educational plan, not a recommendation. No order or stop is changed automatically. Method and sources →

Pattern Analysis

71 setup score
RS Score 48
Trend template 7/8
The Universal Edge Check · context only

What the setup still has going for it, recorded for later. The verdict above stands — these principles do not overrule it.

1/7 universals met
  • A relative-strength leader — not met RS rank 39 — laggard
  • Risk is defined — not met No stop — undefined risk
  • Asymmetric reward — partly met No target set
  • Clear of earnings — partly met Report date unknown
  • Not chasing (in range) — partly met Pivot distance unknown
  • Volume confirms — partly met 0.6× average — light
  • In a confirmed uptrend — met Stage 2 · Trend template 7/8
Why these seven? → The Universal Edge

Minervini Trend Template

7/8

Grades the price structure — moving-average stacking, distance from the 52-week high/low, and relative strength above the ≥70 uptrend bar. This is the technical trend check; the company's fundamentals and ≥80 RS leadership are scored separately in the Grade Card.

Price above SMA 150 & 200 $514.56 vs SMA150 $471.88 / SMA200 $467.58
SMA 150 above SMA 200 SMA150 $471.88 vs SMA200 $467.58
SMA 200 trending up Slope +11.37 over 20 days
SMA 50 above SMA 150 & 200 SMA50 $510.30
Price above SMA 50 $514.56 vs SMA50 $510.30
30%+ above 52-week low +37.5% from $374.17
Within 25% of 52-week high -8.2% from $560.25
RS score above 70 RS 48

Fundamentals

52W Range
75%
Mkt Cap SEC
130.4B
Rev YoY
+9%
EPS TTM
$15.32
P/E TTM
33.6x
Float
253M

Company

Company profile
Vertex Pharmaceuticals Incorporated
VRTX · NASDAQ · Health Technology · Pharmaceuticals: Major

Weekly Context

Multi-timeframe signals from weekly bars
W. Trend
8/8
W. RS
80
W. Support
$412.27
W. Resist
$560.25
Weekly Structure

Scan History

20× streak
Sep 10: 71 (Trend Only)Sep 11: 67 (Trend Only)Sep 11: 68 (Trend Only)Sep 11: 70 (Trend Only)Sep 11: 70 (Trend Only)Sep 11: 71 (Trend Only)71
Sep 11
Trend Only ✓ Gate
71
Sep 11
Trend Only ✓ Gate
70
Sep 11
Trend Only ✓ Gate
70
Sep 11
Trend Only ✓ Gate
68
Sep 11
Trend Only ✓ Gate
67
Sep 10
Trend Only ✓ Gate
71 0.0%

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